Evidence for functional convergence in genes upregulated by herbivores ingesting plant secondary compounds

BMC Ecology

Table 4 Gene ontology (GO) terms overrepresented in (A) naïve N. bryanti and (B) experienced N. bryanti on creosote diets

Ontology	List	Gene set	z-score
A. naïve *N. bryanti*
response to stimulus	61	1241	3.66
response to chemical stimulus	30	533	3.13
system development	28	587	2.06
response to stress	27	525	2.44
immune system process	22	265	4.62
apoptosis	20	350	2.56
cell death	20	367	2.34
death	20	370	2.3
programmed cell death	20	353	2.52
regulation of multicellular organismal process	20	328	2.88
regulation of apoptosis	17	287	2.51
regulation of cell death	17	297	2.35
regulation of programmed cell death	17	289	2.47
cellular response to chemical stimulus	15	222	2.89
immune response	15	140	4.92
regulation of developmental process	15	244	2.5
response to external stimulus	13	189	2.75
regulation of multicellular organismal development	12	206	2.02
defense response	11	147	2.83
positive regulation of developmental process	11	113	3.82
response to wounding	11	137	3.09
hemopoiesis	10	103	3.63
hemopoietic or lymphoid organ development	10	106	3.52
immune system development	10	115	3.23
negative regulation of apoptosis	10	145	2.41
negative regulation of cell death	10	153	2.23
negative regulation of programmed cell death	10	145	2.41
B. experienced *N. bryanti*
metabolic process	96	2711	2.39
small molecule metabolic process	35	782	2.51
response to chemical stimulus	25	533	2.3
cellular ketone metabolic process	23	332	4.23
carboxylic acid metabolic process	22	321	4.07
organic acid metabolic process	22	328	3.96
oxoacid metabolic process	22	321	4.07
amine metabolic process	13	203	2.81
cellular amine metabolic process	12	181	2.82
cellular amino acid metabolic process	11	152	3.02
monocarboxylic acid metabolic process	10	157	2.43

“List” indicates the number of genes highly expressed within the term; “Gene set” indicates the total number of genes in that ontology included on the array.

ISSN: 1472-6785