| |
d.f.
|
AICc
|
ΔAICc
|
Weight
|
Model set
|
|---|
|
FOC
|
|
NG
|
9
|
379.11
|
0.00
|
0.191
|
all
|
|
NG + R2
|
10
|
379.53
|
0.42
|
0.154
|
ii
|
|
NG + R1
|
10
|
380.07
|
0.97
|
0.117
|
ii
|
|
NG + HDRB
|
10
|
381.08
|
1.97
|
0.071
|
i
|
|
NG + sMLH
|
10
|
381.27
|
2.16
|
0.065
|
all
|
|
NG + R3
|
10
|
381.48
|
2.38
|
0.058
|
ii
|
|
NG + R1 + R2
|
11
|
381.61
|
2.51
|
0.054
|
ii
|
|
NG + R2 + R3
|
11
|
381.73
|
2.63
|
0.051
|
ii
|
|
NG + sMLH + R2
|
11
|
381.85
|
2.74
|
0.048
|
ii
|
|
NG + sMLH + R1
|
11
|
382.30
|
3.19
|
0.039
|
ii
|
|
NG + R1 + R3
|
11
|
382.50
|
3.40
|
0.035
|
ii
|
|
NG + sMLH + HDRB
|
11
|
383.26
|
4.16
|
0.024
|
i
|
|
NG + sMLH + R3
|
11
|
383.67
|
4.57
|
0.019
|
ii
|
|
NG + sMLH + R1 + R2
|
12
|
383.96
|
4.85
|
0.017
|
ii
|
|
NG + R1 + R2 + R3
|
12
|
384.00
|
4.90
|
0.016
|
ii
|
|
NG + sMLH + R2 + R3
|
12
|
384.06
|
4.96
|
0.016
|
ii
|
|
NG + sMLH + R1 + R3
|
12
|
384.78
|
5.67
|
0.011
|
ii
|
|
NG + G_DRB1
|
13
|
386.21
|
7.11
|
0.005
|
iii
|
|
NG + sMLH + R1 + R2 + R3
|
13
|
386.38
|
7.27
|
0.005
|
ii
|
|
NG + sMLH + G_DRB1
|
14
|
388.65
|
9.54
|
0.002
|
iii
|
|
FEC
|
|
NG + sMLH + sMLH2 + HDRB
|
8
|
378.34
|
0.00
|
0.298
|
i
|
|
NG + sMLH + sMLH2 + R3
|
8
|
379.61
|
1.28
|
0.158
|
ii
|
|
NG + sMLH + sMLH2 + R1 + R3
|
9
|
380.61
|
2.27
|
0.096
|
ii
|
|
NG + sMLH + sMLH2 + R1 + R2 + R3
|
10
|
381.07
|
2.73
|
0.076
|
ii
|
|
NG + R1 + R3
|
7
|
381.52
|
3.18
|
0.061
|
ii
|
|
NG + R3
|
6
|
381.61
|
3.28
|
0.058
|
ii
|
|
NG + sMLH + sMLH2 + R2 + R3
|
9
|
381.65
|
3.31
|
0.057
|
ii
|
|
NG + HDRB
|
6
|
382.33
|
3.99
|
0.041
|
i
|
|
NG + R1 + R2 + R3
|
8
|
382.44
|
4.11
|
0.038
|
ii
|
|
NG + sMLH + sMLH2
|
7
|
382.90
|
4.56
|
0.030
|
all
|
|
NG + sMLH + sMLH2 + G_ DRB1
|
11
|
383.27
|
4.93
|
0.025
|
iii
|
|
NG + R2 + R3
|
7
|
383.85
|
5.51
|
0.019
|
ii
|
|
NG + G_DRB1
|
9
|
384.73
|
6.40
|
0.012
|
iii
|
|
NG + sMLH + sMLH2 + R1
|
8
|
384.87
|
6.54
|
0.011
|
ii
|
|
NG + sMLH + sMLH2 + R2
|
8
|
385.19
|
6.85
|
0.010
|
ii
|
|
NG + sMLH + sMLH2 + R1 + R2
|
9
|
387.04
|
8.70
|
0.004
|
ii
|
|
NG
|
5
|
387.61
|
9.27
|
0.003
|
all
|
|
NG + R1
|
6
|
389.07
|
10.73
|
0.001
|
ii
|
|
NG + R2
|
6
|
389.63
|
11.30
|
0.001
|
ii
|
|
NG + R1 + R2
|
7
|
391.33
|
12.99
|
0.000
|
ii
|
- Three sets of genetic models have been tested on FOC and FEC including either (i) the effects of sMLH and DRB1 heterozygosity status (HDRB), (ii) the effects of sMLH and the presence of specific DRB1 alleles or (iii) the effects of sMLH and DRB1genotypes (G_DRB1). d.f. are the degree of freedom, weight is the Akaike weight. NG stands for the non-genetic variables retained from the first step of the modeling approach (see Additional file 1). R1, R2 and R3 stand for DRB1 *0324, DRB1*07012 * and DRB1*0114 alleles, respectively
