Both candidate gene and neutral genetic diversity correlate with parasite resistance in female Mediterranean mouflon

Table 2 Model selection of mixed-effects models based on corrected Akaike’s Information Criterion (AICc) for testing the effects of sMLH and DRB1 gene on parasite resistance as measured by FOC and FEC

	d.f.	AICc	ΔAICc	Weight	Model set
FOC
NG	9	379.11	0.00	0.191	all
NG + R2	10	379.53	0.42	0.154	ii
NG + R1	10	380.07	0.97	0.117	ii
NG + HDRB	10	381.08	1.97	0.071	i
NG + sMLH	10	381.27	2.16	0.065	all
NG + R3	10	381.48	2.38	0.058	ii
NG + R1 + R2	11	381.61	2.51	0.054	ii
NG + R2 + R3	11	381.73	2.63	0.051	ii
NG + sMLH + R2	11	381.85	2.74	0.048	ii
NG + sMLH + R1	11	382.30	3.19	0.039	ii
NG + R1 + R3	11	382.50	3.40	0.035	ii
NG + sMLH + HDRB	11	383.26	4.16	0.024	i
NG + sMLH + R3	11	383.67	4.57	0.019	ii
NG + sMLH + R1 + R2	12	383.96	4.85	0.017	ii
NG + R1 + R2 + R3	12	384.00	4.90	0.016	ii
NG + sMLH + R2 + R3	12	384.06	4.96	0.016	ii
NG + sMLH + R1 + R3	12	384.78	5.67	0.011	ii
NG + G_DRB1	13	386.21	7.11	0.005	iii
NG + sMLH + R1 + R2 + R3	13	386.38	7.27	0.005	ii
NG + sMLH + G_DRB1	14	388.65	9.54	0.002	iii
FEC
NG + sMLH + sMLH² + HDRB	8	378.34	0.00	0.298	i
NG + sMLH + sMLH² + R3	8	379.61	1.28	0.158	ii
NG + sMLH + sMLH² + R1 + R3	9	380.61	2.27	0.096	ii
NG + sMLH + sMLH² + R1 + R2 + R3	10	381.07	2.73	0.076	ii
NG + R1 + R3	7	381.52	3.18	0.061	ii
NG + R3	6	381.61	3.28	0.058	ii
NG + sMLH + sMLH² + R2 + R3	9	381.65	3.31	0.057	ii
NG + HDRB	6	382.33	3.99	0.041	i
NG + R1 + R2 + R3	8	382.44	4.11	0.038	ii
NG + sMLH + sMLH²	7	382.90	4.56	0.030	all
NG + sMLH + sMLH² + G_ DRB1	11	383.27	4.93	0.025	iii
NG + R2 + R3	7	383.85	5.51	0.019	ii
NG + G_DRB1	9	384.73	6.40	0.012	iii
NG + sMLH + sMLH² + R1	8	384.87	6.54	0.011	ii
NG + sMLH + sMLH² + R2	8	385.19	6.85	0.010	ii
NG + sMLH + sMLH² + R1 + R2	9	387.04	8.70	0.004	ii
NG	5	387.61	9.27	0.003	all
NG + R1	6	389.07	10.73	0.001	ii
NG + R2	6	389.63	11.30	0.001	ii
NG + R1 + R2	7	391.33	12.99	0.000	ii

Three sets of genetic models have been tested on FOC and FEC including either (i) the effects of sMLH and DRB1 heterozygosity status (HDRB), (ii) the effects of sMLH and the presence of specific DRB1 alleles or (iii) the effects of sMLH and DRB1genotypes (G_DRB1). d.f. are the degree of freedom, weight is the Akaike weight. NG stands for the non-genetic variables retained from the first step of the modeling approach (see Additional file 1). R1, R2 and R3 stand for DRB1 *0324, DRB1*07012 * and DRB1*0114 alleles, respectively

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