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Table 2 Maximum likelihood estimates for the best fit generalized estimating equation pathogen and immunity models

From: Gastrointestinal helminths may affect host susceptibility to anthrax through seasonal immune trade-offs

Response

Coefficients

Estimate ± SE

Wald statistic

p -value

Δ QIC from full model

GIsqrt

Intercept

3.83 ± 0.06

4614

0.000***

20.6

 

Rain2

1.74e-03 ± 3.02e-04

14.7

0.000***

 
 

log2PA

−7.75e-03 ± 7.57e-03

1.02

0.236

 
 

Eos

−2.21e-04 ± 1.18e-04

3.43

0.039*

 
 

IgE

−4.67e-03 ± 3.04e-03

2.28

0.085.

 

PA

Intercept

0.467 ± 0.677

0.48

0.455

17.4

 

Rain2

1.35e-02 ± 4.35e-03

9.66

0.001**

 
 

Age

−1.92e-04 ± 2.02e-04

0.90

0.268

 
 

GIP

−1.03e-04 ± 1.55e-04

0.45

0.478

 
 

Eos

4.00e-03 ± 2.12e-03

3.64

0.034*

 
 

Rain*Eos

−3.57e-05 ± 1.19e-05

9.01

0.002**

 

Ectosqrt

Intercept

−0.064 ± 0.290

0.05

1.000

2.47

 

Rain2

−8.56e-04 ± 3.58e-04

5.70

0.010**

 
 

Age

2.82e-04 ± 9.64e-05

8.57

0.002**

 
 

GIsqrt

1.383-02 ± 5.39e-03

6.42

0.006**

 
 

GIsqrt*Age

−4.58e-06 ± 1.88e-06

5.93

0.009**

 

logEos

Intercept

0.751 ± 0.032

549

0.000***

0.07

 

Rain2

8.21e-04 ± 1.28e-04

41.0

0.000***

 
 

GIP

−1.57e-05 ± 8.09e-06

3.77

0.031*

 
 

Ecto

−3.13e-03 ± 3.15e-03

0.99

0.245

 
 

Monos

9.39e-05 ± 3.67e-05

6.54

0.006**

 

logMonos

Intercept

0.910 ± 0.034

699

0.000***

0.23

 

Rain2

4.41e-04 ± 1.57e-04

7.84

0.003**

 
 

Eos

2.19e-04 ± 8.93e-05

5.99

0.008**

 
 

IgE

−2.62e-03 ± 1.11e-03

5.56

0.012*

 
 

IgG

−9.75e-03 ± 3.89e-03

6.27

0.007**

 
 

Rain*Eos

−7.65e-07 ± 4.40e-07

3.03

0.050.

 

logIgE

Intercept

3.97 ± 0.050

6381

0.000***

2.73

 

Rain2

3.93e-04 ± 2.08e-04

3.57

0.036*

 
 

GIP

−1.32e-05 ± 1.51e-05

0.76

0.3126

 
 

Ecto

−6.76e-03 ± 6.23e-03

1.18

0.2046

 

IgGsqrt

Intercept

2.44 ± 0.181

184

0.000***

0.73

 

Rain2

8.55e-04 ± 4.51e-04

3.60

0.035*

 
 

Age

8.66e-05 ± 4.65e-05

3.47

0.038*

 
 

log2PA

2.26e-02 ± 1.55e-02

2.12

0.095.

 
 

Ecto

−1.96e-02 ± 1.36e-02

2.08

0.098.

 
 

Eos

−2.82e-04 ± 2.14e-04

1.73

0.127

 
 

Monos

−4.57e-04 ± 1.67e-04

7.58

0.003**

 
  1. Note.-. p≤ 0.1; *p≤ 0.05; **p≤ 0.01; ***p≤ 0.001.
  2. GIsqrt = transformed GI parasite count (eggs per gram of feces); PA = presence or absence of an anti-PA antibody titer; Ectosqrt = transformed ectoparasite count; logEos = transformed eosinophil count (cells/μl blood); logMonos = transformed monocyte count (cells/μl blood); logIgE = transformed IgE antibody titer (mg/ml serum); IgGsqrt = transformed IgGb antibody titer (mg/ml serum); Rain2 = amount of rainfall (mm) experienced by an individual in the 60 days prior to sampling; log2PA = log2 of the dilution used to determine the anti-PA antibody titer.